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Amicia (Amicia de Rune) is the young female protagonist in A Plague Tale: Innocence. She and her younger brother Hugo are orphans fleeing the Inquisition and the supernatural appearance of the rats. Her physical prowess isn't that big, but she knows how to defend herself with a slingshot.

Aside from her slingshot, she also will have the ability to sneak around enemies, to avoid their contact.